Which cells synthesize all fibrous elements and elaborate the extracellular matrix?

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Multiple Choice

Which cells synthesize all fibrous elements and elaborate the extracellular matrix?

Fibroblasts are the primary cells that synthesize the fibrous components of the extracellular matrix. They actively produce collagen fibers (types I and III most abundant in connective tissue), elastic fibers, reticular fibers, and the ground substance (proteoglycans, glycosaminoglycans, and glycoproteins) that together form the supportive matrix surrounding cells. This is why they are the main source of all fibrous elements and ECM elaboration in connective tissue.

Other listed cells have different roles: macrophages are immune phagocytes; eosinophils participate in allergic responses and parasite defense; myofibroblasts are contractile cells derived from fibroblasts that appear in wound healing to contract tissue and can contribute to ECM, but the baseline production of most fibrous elements is carried out by fibroblasts.

Which cells synthesize all fibrous elements and elaborate the extracellular matrix?

Study for your anatomy test with Netter's Anatomy Practice Test. Utilize questions and illustrated guides to master human anatomy and ace your exam!

Which cells synthesize all fibrous elements and elaborate the extracellular matrix?

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