Mature bone cells that maintain the bone matrix are called?

• A. Osteocytes
• B. Osteoblasts
• C. Osteoclasts
• D. Osteoprogenitor cells

Answer: (A)

Mature bone cells that maintain the bone matrix are osteocytes. These cells originate when osteoblasts become embedded in the mineralized matrix in tiny cavities called lacunae. Once inside the matrix, osteocytes extend long processes through canaliculi to connect with neighboring cells, forming an intercellular network. This network lets them monitor and regulate mineral content and matrix integrity, respond to mechanical strain, and coordinate local remodeling by signaling to other bone cells when repair or turnover is needed. In contrast, osteoblasts are the active builders that lay down new matrix, osteoclasts resorb bone, and osteoprogenitor cells are stem cells that can differentiate into osteoblasts.